VETENSKAPLIGT PROGRAM - MKON

4385

Research at Uppsala University - Uppsala University, Sweden

Since the introduction of clinical PET/MRI in 2011, it has had some impact (e.g., imaging the components of inflammation in myocardial infarction), but its role could be much greater. Figure 7. Infarction in different vascular territories. (a, b) Two-chamber (a) and shortaxis (b) delayed-enhancement images show near-full-thickness to full-thickness delayed hyperenhancement in the basal, mid, and apical anterior and anteroseptal segments (arrows), in an LAD territory distribution. (c, d) Three-chamber (c) and short-axis (d) delayedenhancement images in another patient show MR imaging was performed to investigate whether Gd-DTPA-BMA-in- duced contrast enhancement of myocardial infarction is counteracted by Dy- DTPA-BMA. Myocardial infarction was induced in 5 pigs. Microdialysate probes were inserted in ischemic and nonischemic myocardium.

Mr imaging of myocardial infarction

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Methods Myocardial infarction was induced by permanent ligation of the left coronary artery in male C57Bl/6 mice. MR imaging was performed at 9.4T (horizontal-bore MR scanner, Varian, Palo Alto, CA, USA) using a quadrature transmit Myocardium from Chronic Myocardial Scar: The Value of Contrast-Enhanced SSFP-Based Cine MR Imaging The purpose of this study is to demonstrate whether the signal intensity (SI) of myocardial infarction (MI) on contrast enhanced (CE)-cine MRI is useful for differ-entiating recently infarcted myocardium from chronic scar. This study included 24 To investigate whether Gd-DTPA-BMA-enhanced MR imaging permits differentiation between reperfused and nonreperfused myocardial infarction, myocardial infarction was induced in 12 domestic pigs. In All animals survived and completed imaging. Infarction was achieved in 18/20 subjects. Fused PET/MR yielded an imaging correlation of elevated FDG tracer activity within regions of myocardial infarction but reduced activity in regions of microvascular obstruction.

Imaging of different parameters has been explored: infarct size with small Gd-chelates [1], cell viability with manganese [2], and apoptotic cells with annexin A5-conjugated contrast agents [3]. To evaluate whether 3T clinical MRI with a small-animal coil and gradient-echo (GE) sequence could be used to characterize long-term left ventricular remodelling (LVR) following nonreperfused myocardial infarction (MI) using semi-automatic segmentation software (SASS) in a rat model.

SweCRIS

Radiology . 2010, 256(2). 415-423.

Annexin A5 reduces infarct size and improves cardiac function

Mr imaging of myocardial infarction

Since the introduction of clinical PET/MRI in 2011, it has had some impact (e.g., imaging the components of inflammation in myocardial infarction), but its role could be much greater.

Mr imaging of myocardial infarction

2009-09-01 · Materials and methods.
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Mr imaging of myocardial infarction

The signal enhancement in MR imaging of normal, infarcted and reperfused myocardium was investigated using different types of contrast agents.

Diagnostic value of precontrast T1 mapping in acute and chronic myocardial infarction. JACC Cardiovasc Imaging.
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Mr imaging of myocardial infarction hantverksakademin i sverige ab
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Annika Isberg - Umeå universitet

Objectives 1. To discuss the role of MR in myocardial infarction. 2. To demonstrate the imaging features of acute and chronic MI. 3.

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Myocardium, MR sity, 600 N Wolfe St, Rm 110-MRI, Bal- timore, MD infarction on magnetic resonance (MR) images by  Sep 11, 2020 Myocardial infarction (MI) remains the leading cause of heart failure and mortality in the modern world [1]. To date, the most effective strategy of  The purpose of the study is to compare two forms of cardiac imaging— echocardiography or “echo,” and MRI—for the detection of blood clots (“thrombi”), which  Among the techniques of nuclear cardiology, myocardial perfusion imaging is the most Explore cardiac imaging modalities like PET, CT & MR and their role in  INTERPRETATION OF CARDIAC MAGNETIC RESONANCE IMAGING. (MRI) In acute myocardial infarction (MI), cardiac MRI is useful in identifying myocardial   Jul 2, 2019 What exactly happens to trigger a heart attack? Learn more from WebMD about causes of heart attack and what to expect afterward. Synonym/Acronym: PYP cardiac scan, infarct scan, pyrophosphate cardiac scan, acute myocardial infarction scan. Rationale To identify myocardial infarcts and  Feb 7, 2009 That's why the right coronary artery (RCA) is usually the culprit artery for an inferior wall MI. But where in the RCA is the occlusion located?

(c, d) Three-chamber (c) and short-axis (d) delayedenhancement images in another patient show 2009-09-01 CARDIAC MR IMAGING is a well established modality in the diagnosis of myocardial infarction (MI) and has the potential to assess viability. Despite this huge potential, MR imaging is of limited access and needs long acquisition times, preventing its use in the positive diagnosis of acute coronary syndromes without ST wave elevation (NSTEMI), which is particularly challenging. Accurate identification of myocardial viability after myocardial infarction with novel manganese chelate-based MR imaging NMR Biomed .